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Antigenic Specificity | NMNAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP (PubMed:17402747). Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency (PubMed:17402747). Can use triazofurin monophosphate (TrMP) as substrate (PubMed:17402747). Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+ (PubMed:17402747). For the pyrophosphorolytic activity, prefers NAD+ and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively (PubMed:17402747). Involved in the synthesis of ATP in the nucleus, together with PARP1, PARG and NUDT5 (PubMed:27257257). Nuclear ATP generation |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human NMNAT1 (NP 073624.2). |
Other Names | [LCA9; NMNAT; PNAT1] |
Gene, Accession # | [NMNAT1], Gene ID: 64802, NCBI: Q9HAN9.1, UniProt: Q9HAN9 |
Catalog # | MBS8546279 |
Price | $280 |
Order / More Info | NMNAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |