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Antigenic Specificity | TET2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TET2 antibody is human and mouse reactive. At least two isoforms of TET2 are known to exist; this antibody will detect the larger isoforms. This antibody is predicted to not cross-react with TET1 and TET3. TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14% of patients with JAK2V617F-positive myeloproliferative neoplasms (1), and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia (2). Analysis of the TET2 and JAK2 mutations in thes |
Immunogen | Immunogen: TET2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET2. Buffer: TET2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TET2; MDS; KIAA1546; Nbla00191; Methylcytosine dioxygenase TET2; tet methylcytosine dioxygenase 2], [TET2; TET2; MDS; KIAA1546; KIAA1546] |
Gene, Accession # | [TET2], Gene ID: 54790, NCBI: NP_001120680, UniProt: Q6N021 |
Catalog # | MBS153684 |
Price | $375 |
Order / More Info | TET2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |