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Antigenic Specificity | CCR3 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively splice |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCR3 |
Other Names | [C-C chemokine receptor type 3 isoform 1; C-C chemokine receptor type 3; C-C chemokine receptor type 3; C-C motif chemokine receptor 3; Eosinophil eotaxin receptor; CD_antigen: CD193] |
Gene, Accession # | [CCR3], Gene ID: 1232, NCBI: NP_001828.1, UniProt: P51677 |
Catalog # | MBS3221496 |
Price | $335 |
Order / More Info | CCR3 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |