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Antigenic Specificity | MEKK4 (Center C1081), 1067-1097 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MEKK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1067-1097 amino acids from the Central region of human MEKK4. The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors. This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 4; MAP three kinase 1; MAPK/ERK kinase kinase 4; MEK kinase 4; MEKK 4; MAP3K4; KIAA0213; MAPKKK4; MEKK4; MTK1] |
Gene, Accession # | [MAP3K4], Gene ID: 4216, NCBI: NP_005913.2, UniProt: Q9Y6R4 |
Catalog # | MBS9206642 |
Price | $165, $370 |
Order / More Info | MEKK4 (Center C1081), 1067-1097 Antibody from MYBIOSOURCE INC. |
Product Specific References | Grucza, R.A., et al. Addict Biol 15(3):346-357(2010) Whitmarsh, A.J., et al. Oncogene 26(22):3172-3184(2007) Aissouni, Y., et al. Biochem. Biophys. Res. Commun. 338(2):808-814(2005) Abell, A.N., et al. J. Biol. Chem. 280(43):35793-35796(2005) Derbyshire, Z.E., et al. Mol. Cell. Biochem. 271 (1-2), 77-90 (2005) : |