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Antigenic Specificity | PTRH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.8 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PTRH2 protein. PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein.During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm.Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. |
Immunogen | Immunogen: Fusion protein of human PTRH2 |
Other Names | [BIT1; PTH2; CFAP37; CGI-147] |
Gene, Accession # | [PTRH2], Gene ID: 51651, NCBI: NP_001015509.1, UniProt: Q9Y3E5 |
Catalog # | MBS9416156 |
Price | $255 |
Order / More Info | PTRH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |