MyoD1 (Rhabdomyosarcoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMyoD1 (Rhabdomyosarcoma Marker)
Clone[SPM427]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, chicken
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilms tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas.
ImmunogenImmunogen: Recombinant mouse MyoD1 protein
Other Names[bHLHc1, Class C basic helix-loop-helix protein 1, Myoblast determination protein 1, Myogenic differentiation 1, Myogenic factor 3 (Myf-3), Myogenin D1, PUM], [MYOD1; MYOD1; PUM; MYF3; MYOD; bHLHc1; BHLHC1; MYF3; MYOD; bHLHc1; Myf-3]
Gene, Accession #[MYOD1], Gene ID: 4654, NCBI: NP_002469.2, UniProt: P15172
Catalog #MBS438339
Price$190, $340, $340
Order / More InfoMyoD1 (Rhabdomyosarcoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesThulasi R et. al. Cell Growth and Differentiation, 1996, 7(4):531-41. Wesche WA et. al. American Journal of Surgical Pathology, 1995, 19(3):261-9. Parham DM et. al. Acta Neuropathologica, 1994, 87:605-11
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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