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Antigenic Specificity | MyoD1 (Rhabdomyosarcoma Marker) |
Clone | [SPM427] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, chicken |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilms tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas. |
Immunogen | Immunogen: Recombinant mouse MyoD1 protein |
Other Names | [bHLHc1, Class C basic helix-loop-helix protein 1, Myoblast determination protein 1, Myogenic differentiation 1, Myogenic factor 3 (Myf-3), Myogenin D1, PUM], [MYOD1; MYOD1; PUM; MYF3; MYOD; bHLHc1; BHLHC1; MYF3; MYOD; bHLHc1; Myf-3] |
Gene, Accession # | [MYOD1], Gene ID: 4654, NCBI: NP_002469.2, UniProt: P15172 |
Catalog # | MBS438339 |
Price | $190, $340, $340 |
Order / More Info | MyoD1 (Rhabdomyosarcoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Thulasi R et. al. Cell Growth and Differentiation, 1996, 7(4):531-41. Wesche WA et. al. American Journal of Surgical Pathology, 1995, 19(3):261-9. Parham DM et. al. Acta Neuropathologica, 1994, 87:605-11 |