Smad4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySmad4
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 4(SMAD4) detection. Tested with WB in Human;Mouse;Rat. Background: SMAD4 (Mothers Against Decapentaplegic Drosophila Homolog of 4), also known as MADH4 or DPC4, is a protein that in humans is encoded by the SMAD4 gene. It belongs to the Darfwin family of proteins that modulate members of the TGFbeta protein superfamily. Hahn et al. (1996) identified the SMAD4 gene on chromosome 18q21.1. Howe et al. (1998) identified the SMAD4 gene within a region on 18q21.1 defined by linkage analysis in kindred with juvenile polyposis syndrome. To test directly the hypothesis that the SMAD4 gene is a tumor suppressor that is critical for transmitting signals from transf
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Smad4 (526-552aa EIHLHRALQLLDEVLHTMPIADPQPLD), identical to the related mouse and rat sequences. Ig Type: Rabbit IgG
Other Names[Mothers against decapentaplegic homolog 4; (Small) Mothers Against Decapentaplegic; Deleted in Pancreatic Carcinoma; Deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; DPC 4; DPC4; hSMAD4; JIP; MAD homolog 4; MAD mothers against decapentaplegic Drosophila homolog 4; MAD mothers against decapentaplegic homolog 4; MADH 4; MADH4; Med; Medea; Mothers against decapentaplegic homolog 4; Mothers against DPP homolog 4; OTTHUMP00000163548; SMAD 4; SMAD family member 4; SMAD mothers against DPP homolog 4; Smad4; SMAD4_HUMAN; SMAD family member 4], [SMAD4; SMAD4; JIP; DPC4; MADH4; MYHRS; DPC4; MADH4; MAD homolog 4; Mothers against DPP homolog 4; SMAD 4; Smad4; hSMAD4]
Gene, Accession #[SMAD4], Gene ID: 4089, NCBI: NP_005350.1, UniProt: Q13485
Catalog #MBS177924
Price$280
Order / More InfoSmad4 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hein, L.; Altman, J. D.; Kobilka, B. K. :Two functionally distinct alpha-2-adrenergic receptors regulate sympathetic neurotransmission. Nature 402: 181-184, 1999. 2. Hoehe, M. R.; Berrettini, W. H.; Lentes, K.-U.:Dra I identifies a two allele DNA polymorphism in the human alpha-2-adrenergic receptor gene (ADRAR), using a 5.5 kb probe (p ADRAR). Nucleic Acids Res. 16: 9070 only, 1988. 3. Yang-Feng, T. L.; Kobilka, B. K.; Caron, M. G.; Lefkowitz, R. J.; Francke, U.:Chromosomal assignment of genes for an alpha-adrenergic receptor (ADRAR) and for another member of this receptor family coupled to guanine nucleotide regulatory proteins (RG21). (Abstract) Cytogenet. Cell Genet. 46: 722-723, 1987.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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