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Antigenic Specificity | FGF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FGF2 antibody detects endogenous levels of total FGF2. Description: Fibroblast growth factors are a family of broad-spectrum growth factors influencing a plethora of cellular activities. The interaction of at least 23 ligands, 4 receptors and multiple coreceptors provides a dramatic complexity to a signaling system capable of effecting a multitude of responses (1, 2). Basic fibroblast growth factor (bFGF or FGF2), initially identified as a mitogen with prominent angiogenic properties, is now recognized as a multifunctional growth factor (3). It is clear that bFGF produces its biological effects in target cells by signaling through cell-surface FGF receptors. bFGF binds to all four FGF receptors. Ligand binding induces receptor |
Immunogen | Immunogen: N term-peptide of human FGF2 Subcellular Location: Secreted. Nucleus. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and |
Other Names | [Basic fibroblast growth factor; Basic fibroblast growth factor bFGF; BFGF; FGF 2; FGF B; FGF-2; Fgf2; FGF2 basic; FGF2_HUMAN; FGFB; Fibroblast growth factor 2 (basic); Fibroblast growth factor 2; Fibroblast growth factor, basic; HBGF 2; HBGF-2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; Heparin-binding growth factor 2; Prostatropin] |
Gene, Accession # | [FGF2], Gene ID: 2247, NCBI: NP_001997.5, UniProt: P09038 |
Catalog # | MBS9606704 |
Price | $240, $280 |
Order / More Info | FGF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen W, Chen J, Xu M, Zhong Z, Zhang Q, Yang W, Huang G; Journal: Biol Reprod. Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation. Zhang Y, Chen Z, Wang T, Yang J, Li R, Wang S, Liu J, Ye Z; Journal: Oncotarget. Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase. Yin LL, Wen XM, Lai QH, Li J, Wang XW; Journal: Oncol Lett. Lenalidomide improvement of cisplatin antitumor efficacy on triple-negative breast cancer cells in vitro. |