Edit |   |
---|---|
Antigenic Specificity | PAR4 |
Clone | [3G9H7; 4H12E9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcrip |
Immunogen | Immunogen: Purified recombinant fragment of PAR4 (aa1-330) expressed in E Coli. |
Other Names | [PAWR], [PAWR] |
Gene, Accession # | [PAR4], Gene ID: 5074 |
Catalog # | MBS475813 |
Price | $335 |
Order / More Info | PAR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |