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Antigenic Specificity | GATA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1.0 mg/ml |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti GATA1 antibody recognizes GATA1, also known as GATA binding factor 1. The protein is a member of the GATA family of transcription factors, which has received its name from binding DNA containing the GATA consensus motif 5'-[AT]GATA[AG]-3' (uniprot P15976). GATA1 acts as an erythroid transcription factor by regulating erythroid-specific genes. In addition to that, GATA1 has also been implied to play a role in regulating differentiation of other hematopoietic lineages (including mast cells and megakaryocytes) and endothelial cells (Orkin 1992). GATA1 alterations have been implicated in a variety of diseases, including acute megakaryoblastic leukemia (AMKL) associated with Trisomy 21 and thrombocytopenia (Ciovacco et al. 2008). |
Immunogen | Immunogen: N-terminal truncated human recombinant protein |
Other Names | [GATA1], [GATA1; GATA1; GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1; ERYF1; GF1; GATA-1; GF-1] |
Gene, Accession # | [GATA1], Gene ID: 2623, NCBI: P15976.1, UniProt: P15976 |
Catalog # | MBS225048 |
Price | $470 |
Order / More Info | GATA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |