Edit |   |
---|---|
Antigenic Specificity | HRAS/KRAS/NRAS |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
Immunogen | Immunogen: Recombinant protein of human NRAS |
Other Names | [NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1] |
Gene, Accession # | [HRAS/KRAS/NRAS], Gene ID: 3265, NCBI: P01112.1, UniProt: P01112 |
Catalog # | MBS9131296 |
Price | $235, $350, $525 |
Order / More Info | HRAS/KRAS/NRAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |