CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD40
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey, porcine
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration200 ug/ml
ApplicationsWestern Blot (WB)
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DescriptionCD40 is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand, a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with T cells expressing CD40L, and activation of CD4+ T cells. In non-hemopoitic cells such as epidermal basal cells, CD40 ligation serves as the signal for inhibition of cell growth and induction of differentiation. The cytoplasmic domain of CD40 interacts with TRAF6, a TNFR associated factor homolog that mediates signaling from CD40. Ligation of CD40 with its ligand preferentially
ImmunogenImmunogen: CD40 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acids 261 of human CD40 as the immunogen.
Other Names[Rabbit CD40; CD40; CD40; CD-40; CDW40; p50; CD40; Bp50; CD-40; CD 40; CD 40; MGC9013; TNFRSF5; CDw40]
Gene, Accession #[CD40], Gene ID: 21939
Catalog #MBS5311153
Price$465
Order / More InfoCD40 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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