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Antigenic Specificity | LAT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total LAT2 protein. This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human linker for activation of T cells family, member 2 |
Other Names | [LAB; NTAL; WSCR5; WBSCR5; HSPC046; WBSCR15] |
Gene, Accession # | [LAT2], Gene ID: 7462, NCBI: NP_054865.2, UniProt: Q9GZY6 |
Catalog # | MBS9409482 |
Price | $255 |
Order / More Info | LAT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |