CD31 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD31 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis (1). CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members (2). The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLCgamma and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules (3). |
| Immunogen | Immunogen: Recombinant protein of human CD31 |
| Other Names | [PECAM1; CD31; CD31; PECAM1; CD31; FLJ34100; FLJ58394; PECAM-1; EndoCAM; GPIIA; PECA1;], [PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1] |
| Gene, Accession # | Gene ID: 5175, NCBI: NP_000433.4, UniProt: P16284 |
| Catalog # | MBS125831 |
| Price | $200, $275, $430 |
| Order / More Info | CD31 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Newman, P.J. (1997) J. Clin. Invest. 99, 3-8. 2. Cao, M. Y. et al. (1998) J. Biol. Chem. 273, 15765-15772. 3. Ilan, N. and Madri, J.A. (2003) Curr. Opin. Cell Biol. 15, 515-524. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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