GCLM Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GCLM antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GCLM |
| Clone | [AT2D12] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer. |
| Immunogen | Immunogen: Recombinant human GCLM (1-274aa) purified from E. coli |
| Other Names | [Glutamate-cysteine ligase modifier subunit; Glutamate-cysteine ligase; modifier subunit; GLCLR], [GCLM; GCLM; GLCLR; GLCLR] |
| Gene, Accession # | [GCLM], Gene ID: 2730, NCBI: NP_002052, UniProt: P48507 |
| Catalog # | MBS200243 |
| Price | $240, $315 |
| Order / More Info | GCLM Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dickinson D.A., et al. (2005) Free Radic Biol Med 37 (8): 1152-1159; Inoue Y., et al. (2003) Int J Oncol 23 (5): 1333-1339; Robertson N.G., et al. (1995) Genomics 23 (1): 42-50 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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