Edit |   |
---|---|
Antigenic Specificity | NEFL |
Clone | [1H3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
Immunogen | Immunogen: Purified recombinant fragment of human NEFL expressed in E. Coli. |
Other Names | [NFL; NF-L; NF68; CMT1F; CMT2E] |
Gene, Accession # | [NEFL], Gene ID: 4747, NCBI: P07196.3, UniProt: P07196 |
Catalog # | MBS8538859 |
Price | $280 |
Order / More Info | NEFL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |