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Antigenic Specificity | ADRA2A (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ADRA2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-152 amino acids from human ADRA2A. Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, ADRA2A, ADRA2R, ADRAR] |
Gene, Accession # | [ADRA2A], Gene ID: 150, NCBI: NP_000672.3, UniProt: P08913 |
Catalog # | MBS9216662 |
Price | $165, $370 |
Order / More Info | ADRA2A (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kobilka B.K.,et al.Science 238:650-656(1987).Fraser C.M.,et al.J. Biol. Chem. 264:11754-11761(1989).Guyer C.A.,et al.J. Biol. Chem. 265:17307-17317(1990).Small K.M.,et al.J. Biol. Chem. 275:38518-38523(2000).Small K.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 103:5472-5477(2006). |