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Antigenic Specificity | RUSC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1. RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide from near the carboxy terminus of human RUSC2. |
Other Names | [RUN and SH3 domain containing protein 2, Iporin] |
Gene, Accession # | [RUSC2], Gene ID: 23623, NCBI: NP_001098673 |
Catalog # | MBS9401241 |
Price | $320 |
Order / More Info | RUSC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |