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Antigenic Specificity | PDE3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PDE3B protein. PDE3B (Phosphodiesterase 3B) is a Protein Coding gene. Diseases associated with PDE3B include Pseudohypoparathyroidism, Type Ii and Pelizaeus-Merzbacher Disease. Among its related pathways are G alpha(s) signalling events and Akt Signaling. Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PDE3B protein |
Other Names | [Rabbit PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B] |
Gene, Accession # | [PDE3B], Gene ID: 5140, NCBI: AAI44249.1, UniProt: Q13370 |
Catalog # | MBS9710413 |
Price | $130, $220, $325 |
Order / More Info | PDE3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |