Edit |   |
---|---|
Antigenic Specificity | SYT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using SYT1 antibody. Immunofluorescence analysis of HeLa cell using SYT1 antibody. Blue: DAPI for nuclear staining. Synaptotagmin 1 (SYT1) is an integral membrane protein found in synaptic vesicles thought to play a role in vesicle trafficking and exocytosis (1). Individual SYT1 proteins are composed of an amino-terminal transmembrane region, a central linker region and a pair of carboxy-terminal C2 domains responsible for binding Ca2+ (2). The C2 domains appear to be functionally distinct, with the C2A domain responsible for regulating synaptic vesicle fusion in a calcium-dependent manner during exocytosis while the C2B domain allows for interaction between adjacent SYT1 |
Immunogen | Immunogen: Recombinant protein of human SYT1 |
Other Names | [SYT1, partial; SYT1; SYT1], [SYT1] |
Gene, Accession # | [SYT1], NCBI: JAO98031.1 |
Catalog # | MBS419490 |
Price | $385 |
Order / More Info | SYT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |