ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motifs 4) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motifs 4)
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
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DescriptionRecognizes human ADAMTS4. Shows ~10% crossreactivity with recombinant human ADAMTS5 and <1% crossreactivity with recombinant human ADAMTS13, ADAMTS­L1.2 and ADAMTS1 in Western Blot and ELISA. ADAMTS4 is a member of the family of secreted zinc proteases with a multi-domain structure (1-3). The protein precursors consist of a signal peptide and the following domains: pro, catalytic, disintegrin-like, TS type 1 motif, cysteine-rich and spacer. It is the only ADAMTS identified that has one TS type I motif. It is an active protease effectively cleaving alpha-2-macroglobulin and aggrecan at multiple sites, and is inhibited by TIMP-3 with inhibition constants in subnanomolar range (4-6). It receives great attention due to the elevation in its
ImmunogenImmunogen: Recombinant corresponding to Phe213-Cys685 from human ADAMTS4 expressedin CHO cells (O75173).
Other Names[-ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motifs 4)], [ADAMTS4; ADAMTS4; ADMP-1; ADAMTS-2; ADAMTS-4; KIAA0688; KIAA0688]
Gene, Accession #Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173
Catalog #MBS620136
Price$765
Order / More InfoADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motifs 4) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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