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Antigenic Specificity | DCTN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using DCTN2 antibody. Immunofluorescence analysis of U2OS cell using DCTN2 antibody. Blue: DAPI for nuclear staining. Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsib |
Immunogen | Immunogen: Recombinant protein of human DCTN2 |
Other Names | [dynactin subunit 2 isoform 1; dynactin subunit 2; dynactin subunit 2] |
Gene, Accession # | [DCTN2], Gene ID: 10540, NCBI: NP_006391.1 |
Catalog # | MBS4150049 |
Price | $385 |
Order / More Info | DCTN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |