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Antigenic Specificity | RNF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of RNF6 protein. RNF6 (Ring Finger Protein 6) is a Protein Coding gene. Diseases associated with RNF6 include Esophageal Cancer and Squamous Cell Carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and Androgen receptor signaling pathway. The protein encoded by RNF6 contains a RING-H2 finger motif. Deletions and mutations in RNF6 were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same |
Immunogen | Immunogen: Synthesized peptide derived from part region of human RNF6 protein at amino acid sequence of 470-550 |
Other Names | [Rabbit RNF6; E3 ubiquitin-protein ligase RNF6; RING-type E3 ubiquitin transferase RNF6] |
Gene, Accession # | [RNF6], Gene ID: 6049, NCBI: NP_005968, UniProt: Q9Y252 |
Catalog # | MBS9710760 |
Price | $130, $220, $325 |
Order / More Info | RNF6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |