GSK3beta Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GSK3beta antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | GSK3beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin (1). GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3K/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3alpha and Ser9 of GSK-3beta (2,3). GSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus, and mammalian development (4). GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization (5). |
| Immunogen | Immunogen: A synthetic -peptide of human GSK-3beta |
| Other Names | [GSK3B; GSK-3beta; GSK-3b; GSK3B; GSK-3beta;], [GSK3B; GSK3B; GSK-3 beta] |
| Gene, Accession # | Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
| Catalog # | MBS126089 |
| Price | $235, $350, $525 |
| Order / More Info | GSK3beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Welsh, G.I. et al. (1996) Trends Cell. Biol. 6, 274-279. 2. Srivastava, A.K. and Pandey, S.K. (1998) Mol. Cell. Biochem. 182, 135-141. 3. Cross, D.A. et al. (1995) Nature 378, 785-789. 4. Nusse, R. (1997) Cell 89, 321-323. 5. Diehl, J.A. et al. (1998) Genes Dev. 12, 3499-3511. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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