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Antigenic Specificity | XRCC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: XRCC3 antibody detects endogenous levels of total XRCC3. Description: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]Function: Involved in the homologous recombination repair (HRR) pa |
Immunogen | Immunogen: A synthesized peptide derived from human XRCC3 Subcellular Location: Nucleus. Cytoplasm. Cytoplasm > Perinuclear Region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair. Tissue Specificity: Stress-induced increase in the mitochondrial levels is seen. |
Other Names | [CMM6; DNA repair protein XRCC3; RAD51 like; X ray repair complementing defective repair in Chinese hamster; X ray repair complementing defective repair in Chinese hamster cells 3; X ray repair cross complementing protein 3; X-ray repair cross-complementing protein 3; XRCC 3; XRCC3; XRCC3_HUMAN] |
Gene, Accession # | [XRCC3], Gene ID: 7517, NCBI: NP_001093588.1, UniProt: O43542 |
Catalog # | MBS9607510 |
Price | $240, $280 |
Order / More Info | XRCC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |