Caspase 8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Caspase 8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | Peptide ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fract |
| Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
| Other Names | [Homo sapiens caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant B, mRNA; Caspase-8; caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; ICE-like apoptotic protease 5; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MORT1-associated ced-3 homolog; apoptotic cysteine protease; apoptotic protease Mch-5; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE], [CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8] |
| Gene, Accession # | Gene ID: 841, NCBI: NP_203519.1 |
| Catalog # | MBS416400 |
| Price | $230 |
| Order / More Info | Caspase 8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | (1) Wang,L., Du,F. and Wang,X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133 (4), 693-703 (2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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