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Antigenic Specificity | FER |
Clone | [1457CT181.12.17] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1,k |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FER antibody is generated from a mouse immunized with a recombinant protein. Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-m |
Immunogen | n/a |
Other Names | [Tyrosine-protein kinase Fer; Feline encephalitis virus-related kinase FER; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; Proto-oncogene c-Fer; Tyrosine kinase 3; p94-Fer; FER; TYK3] |
Gene, Accession # | [FER], Gene ID: 2241, NCBI: NP_005237.2, UniProt: P16591 |
Catalog # | MBS9200570 |
Price | $165, $370 |
Order / More Info | FER Antibody from MYBIOSOURCE INC. |
Product Specific References | Hao Q.-L.,et al.Mol. Cell. Biol. 9:1587-1593(1989). Makovski A.,et al.J. Biol. Chem. 287:6100-6112(2012). Ota T.,et al.Nat. Genet. 36:40-45(2004). Schmutz J.,et al.Nature 431:268-274(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |