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Antigenic Specificity | CD22 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CD22. It was validated on Western BlotTarget Description: CD22 mediates B-cell B-cell interactions. CD22 may be involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins; one of which is CD45. CD22 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response CD22 seems to be involved in regulation of B-cell antigen receptor signaling. CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruitin |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CD22 |
Other Names | [B-cell receptor CD22 isoform 1; B-cell receptor CD22; B-cell receptor CD22; CD22 molecule; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14] |
Gene, Accession # | [CD22], Gene ID: 933, NCBI: NP_001762, UniProt: P20273 |
Catalog # | MBS3214543 |
Price | $335 |
Order / More Info | CD22 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |