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Antigenic Specificity | PFN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The dynamic polymerization and depolymerization of actin filaments, a process governed by external and internal signaling events, is vital for cell motility (immune cell function, migration, invasion, metastasis, angiogenesis), cell division and adhesion. Among the many regulators of actin dynamics are profilins. Profilins are conserved actin binding proteins that affect the rate of actin polymerization by binding actin monomers and promoting the exchange of ADP for ATP (reviewed in 1). Profilins bind to proteins involved in the regulation of actin dynamics including palladin (2), dynamin-1 (3), VASP (4) and N-WASP (5). In mice, knockout of the ubiquitously expressed profilin-1 indicates that the protein is essential for embryonic developme |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [ALS18; PFN1], [PFN1; PFN1; ALS18] |
Gene, Accession # | [PFN1], Gene ID: 5216, NCBI: P07737.2, UniProt: P07737 |
Catalog # | MBS126375 |
Price | $200, $275, $430 |
Order / More Info | PFN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |