Edit |   |
---|---|
Antigenic Specificity | CD300LB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD300LB antibody detects endogenous levels of total CD300LB. Function: Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.Subunit Structure: Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.Post-translational Modifications: Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.Similarity: Belongs to the CD300 family. |
Immunogen | Immunogen: A synthesized peptide derived from human CD300LB Subcellular Location: Cell Membrane Tissue Specificity: Expressed exclusively in myeloid lineages. |
Other Names | [CD_antigen=CD300b; CD300 antigen-like family member B; CD300 molecule-like family member b; CD300B; CLM 7; CLM7; CLM7_HUMAN; CMRF35 A2; CMRF35-like molecule 7; CMRF35A2; Immune receptor expressed on myeloid cells 3; IREM 3; IREM3; Leukocyte mono-Ig-like receptor 5; LMIR5; TREM 5; TREM5; Triggering receptor expressed on myeloid cells 5; UNQ2530/PRO6029] |
Gene, Accession # | [CD300LB], Gene ID: 124599, NCBI: NP_777552.3, UniProt: A8K4G0 |
Catalog # | MBS9603015 |
Price | $240, $280 |
Order / More Info | CD300LB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |