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Antigenic Specificity | OCT4 (OCT3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect Oct4/Oct3 in human samples. Background: Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation. Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker. Oct-4 exists as two splice variants, Oct-4A and Oct-4B. Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells. |
Immunogen | Immunogen: This OCT4 (OCT3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-141 amino acids from human OCT4 (OCT3). Positive Control: Western blot: HL-60 cell lysate, IF: Sy5Y cells |
Other Names | [POU5F1; OCT3; OCT4; OTF3; POU domain; class 5; transcription factor 1; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3], [POU5F1; POU5F1; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; OCT3; OCT4; OTF3; Oct-3; Oct-4; OTF-3] |
Gene, Accession # | [OCT4 (OCT3)], Gene ID: 5460, NCBI: NP_001272916.1, UniProt: Q01860 |
Catalog # | MBS840494 |
Price | $305 |
Order / More Info | OCT4 (OCT3) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |