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Antigenic Specificity | mGluR2/3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: mGluR2/3 antibody detects endogenous levels of total mGluR2/3. Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.Subunit Structure: Interacts with GRASP (By similarity). Interacts with HTR2A.Similarity: Belongs to the G-protein coupled receptor 3 family. |
Immunogen | Immunogen: A synthesized peptide derived from human mGluR2/3 Subcellular Location: Cell Membrane Tissue Specificity: Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. |
Other Names | [AMPA selective glutamate receptor 2; GLUR2; GLURB; Glutamate metabotropic receptor 2; Glutamate receptor homolog; Glutamate receptor metabotropic 2; GPRC1B; GRM2; GRM2_HUMAN; Metabotropic glutamate receptor 2; mGlu2; mGluR2; OTTHUMP00000210984; OTTHUMP00000210986; GLUR3; Glutamate metabotropic receptor 3; Glutamate receptor metabotropic 3; GPRC1C; GRM3; GRM3_HUMAN; Metabotropic glutamate receptor 3; MGlu3; mGluR3] |
Gene, Accession # | [mGluR2/3], Gene ID: 2912, NCBI: NP_000830.2, UniProt: Q14416 |
Catalog # | MBS9600105 |
Price | $240, $280 |
Order / More Info | mGluR2/3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |