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Antigenic Specificity | CD43 (T-Cell Marker) |
Clone | [SPM503] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. |
Immunogen | Immunogen: Myeloblastic KG1 cells |
Other Names | [Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN], [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP] |
Gene, Accession # | [SPN], Gene ID: 6693, NCBI: NP_001025459.1, UniProt: P16150 |
Catalog # | MBS438195 |
Price | $190, $340, $340 |
Order / More Info | CD43 (T-Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Stross WP, et. al. Journal of Clinical Pathology, 1989, 42(9):953-61 |