CD43 (T-Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD43 (T-Cell Marker)
Clone[SPM503]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
ImmunogenImmunogen: Myeloblastic KG1 cells
Other Names[Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN], [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP]
Gene, Accession #[SPN], Gene ID: 6693, NCBI: NP_001025459.1, UniProt: P16150
Catalog #MBS438195
Price$190, $340, $340
Order / More InfoCD43 (T-Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStross WP, et. al. Journal of Clinical Pathology, 1989, 42(9):953-61
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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