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Antigenic Specificity | Survivin (Phospho-Thr117) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of Survivin only when phosphorylated at Threonine 117. Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Threonine 117 |
Other Names | [API4, EPR-1,] |
Gene, Accession # | Gene ID: 332, NCBI: NP_001012270.1, UniProt: O15392 |
Catalog # | MBS9402159 |
Price | $200, $255 |
Order / More Info | Survivin (Phospho-Thr117) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |