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Antigenic Specificity | ASGR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. This gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this |
Immunogen | Immunogen: Rabbit polyclonal ASGR2 (1) antibody was raised against a recombinate human ASGR2 protein 106-286aa (BC017251). |
Other Names | [Homo sapiens asialoglycoprotein receptor 2, mRNA; Asialoglycoprotein receptor 2; asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; HBxAg-binding protein; hepatic lectin H2; asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2], [ASGR2; ASGR2; HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2] |
Gene, Accession # | [ASGR2], Gene ID: 433, NCBI: BC017251 |
Catalog # | MBS417319 |
Price | $230 |
Order / More Info | ASGR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Guy,C.S., Rankin,S.L. and Michalak,T.I. Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor. Hepatology 54 (3), 1043-1050 (2011) |