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Antigenic Specificity | Human Transcriptional enhancer factor TEF-3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcrip |
Immunogen | Immunogen: Recombinant human Transcriptional enhancer factor TEF-3 protein(74-434aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-292764 / sc-134071 |
Other Names | [TEA domain family member 4; Transcription factor 13-like 1; Transcription factor RTEF-1; RTEF1; TCF13L1; TEAD4], [TEAD4; TEAD4; TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; TCF13L1; hRTEF-1B; RTEF1; TCF13L1; TEF3; TEAD-4] |
Gene, Accession # | [TEF3], Gene ID: 7004, NCBI: NP_003204.2, UniProt: Q15561 |
Catalog # | MBS1496591 |
Price | $160, $235 |
Order / More Info | Human Transcriptional enhancer factor TEF-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |