Human Transcriptional enhancer factor TEF-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Transcriptional enhancer factor TEF-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionTranscription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcrip
ImmunogenImmunogen: Recombinant human Transcriptional enhancer factor TEF-3 protein(74-434aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-292764 / sc-134071
Other Names[TEA domain family member 4; Transcription factor 13-like 1; Transcription factor RTEF-1; RTEF1; TCF13L1; TEAD4], [TEAD4; TEAD4; TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; TCF13L1; hRTEF-1B; RTEF1; TCF13L1; TEF3; TEAD-4]
Gene, Accession #[TEF3], Gene ID: 7004, NCBI: NP_003204.2, UniProt: Q15561
Catalog #MBS1496591
Price$160, $235
Order / More InfoHuman Transcriptional enhancer factor TEF-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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