Edit |   |
Antigenic Specificity | TrkA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for High affinity nerve growth factor receptor(NTRK1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Trk A(Neurotrophic tyrosine kinase receptor A) is the high affinity catalytic receptor for the neurotrophin, Nerve Growth Factor(NGF). Higher affinity binding of NGFR can achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA(NTRK1), TRKB(NTRK2), and TRKC(NTRK3). TRKA, TRKB, and TRKC are specific for or preferred by NGF, NTF4(Neurotrophin-4) and BDNF, and NTF3(Neurotrophin-3), respectively. NTF3 also binds to TRKA and TRKB, but with significantly lower affinity. The absence of TrkA(NGFR) expression |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TrkA (342-361aa RHGCLRLNQPTHVNNGNYTL), identical to the related rat and mouse sequences. |
Other Names | [High affinity nerve growth factor receptor; neurotrophic tyrosine kinase, receptor, type 1; CIPA; DKFZp781I14186; gp140trk; High affinity nerve growth factor receptor; High affinity nerve growth factor receptor precursor; MTC; neurotrophic tyrosine kinase receptor type 1; Ntrk 1; Ntrk1; NTRK1_HUMAN; Oncogene TRK; p140 TrkA; p140-TrkA; TRK 1; Trk A; TRK; Trk-A; TRK1; TRK1 transforming tyrosine kinase protein; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor A; Tyrosine kinase receptor; Tyrosine Receptor Kinase A], [NTRK1; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; MTC; TRK; TRKA; Trk-A] |
Gene, Accession # | [NTRK1], Gene ID: 4914, NCBI: P04629.4, UniProt: P04629 |
Catalog # | MBS175522 |
Price | $315 |
Order / More Info | TrkA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |