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Antigenic Specificity | SNCA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SNCA antibody is human, mouse and rat reactive. At least three isoforms of SNCA are known to exist. Alpha-Synuclein (SNCA) is a hallmark of Alzheimer's disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson's disease (4,5). |
Immunogen | Immunogen: SNCA antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SNCA. The immunogen is located within the last 50 amino acids of SNCA. Buffer: SNCA antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SNCA; PD1; NACP; PARK1; PARK4; Alpha-synuclein; Non-A beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor)], [SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: NP_000336, UniProt: P37840 |
Catalog # | MBS153543 |
Price | $375 |
Order / More Info | SNCA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |