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Antigenic Specificity | SPHK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1 mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human SPHK1 |
Other Names | [SK 1; SK1; Sphingosine kinase 1; SPHK 1; SPHK; Sphk1; SPHK1; SPK; SPK 1] |
Gene, Accession # | [SPHK1], Gene ID: 8877, NCBI: NP_001136073.1, UniProt: Q9NYA1 |
Catalog # | MBS2554400 |
Price | $150, $225, $360 |
Order / More Info | SPHK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |