Edit |   |
---|---|
Antigenic Specificity | TAGL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of TAGL protein. TAGLN encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the |
Immunogen | Immunogen: Synthesized peptide derived from part region of human TAGL protein |
Other Names | [Rabbit TAGL; Transgelin; 22 kDa actin-binding protein; Protein WS3-10; Smooth muscle protein 22-alpha; SM22-alpha] |
Gene, Accession # | [TAGL], Gene ID: 6876, NCBI: NP_001001522.1, UniProt: Q01995 |
Catalog # | MBS9711141 |
Price | $130, $220, $325 |
Order / More Info | TAGL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |