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Antigenic Specificity | CNOT7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein. CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of CNOT7 results in multiple transcript variants. Related pseudogenes have been i |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human CNOT7 at AA range: 10-90 |
Other Names | [Rabbit CNOT7; CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1] |
Gene, Accession # | [CNOT7], Gene ID: 29883, NCBI: NP_037486.2, UniProt: Q9UIV1 |
Catalog # | MBS9701736 |
Price | $130, $220, $325 |
Order / More Info | CNOT7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |