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Antigenic Specificity | HES7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HES7 protein. Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.Kusuhara M., Biomed. Res. 20:273-279(1999).Wittmann B.M., Cancer Res. 63:5151-5158(2003).Ouchida R., Genes Cells 8:95-107(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human HES7. |
Other Names | [Protein HEXIM1; Hexamethylene bis-acetamide-inducible protein 1; Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; Menage a quatre protein 1] |
Gene, Accession # | [HES7], Gene ID: 10614, NCBI: NP_006451.1, UniProt: O94992 |
Catalog # | MBS9410931 |
Price | $200, $255 |
Order / More Info | HES7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |