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Antigenic Specificity | Human CD123 |
Clone | [4A6H6] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD123 is the 70 kD transmembrane alpha chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common beta chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the beta chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
Immunogen | n/a |
Other Names | [cell division cycle protein 123 homolog; cell division cycle protein 123 homolog] |
Gene, Accession # | [CD123], Gene ID: 100528235, NCBI: NP_001187434.1 |
Catalog # | MBS8504000 |
Price | $280, $300 |
Order / More Info | Human CD123 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hausmann OV et al, . (2011) Allergy 66(1):85-91. 2. Giannelli S et al, . (2008) Cytometry B Clin Cytom 74(6):349-55. 3. Arpinati M et al, . (2002) Bone Marrow Transplant. 2002 Jun; 29(11):887-91. |