CENTG1 (C-term), 850-877 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CENTG1 (C-term), 850-877 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.25 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CENTG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 850-877 amino acids from the C-terminal region of human CENTG1. GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficki |
| Immunogen | n/a |
| Other Names | [Arf-GAP with GTPase; ANK repeat and PH domain-containing protein 2; AGAP-2; Centaurin-gamma-1; Cnt-g1; GTP-binding and GTPase-activating protein 2; GGAP2; Phosphatidylinositol 3-kinase enhancer; PIKE; AGAP2; CENTG1; KIAA0167] |
| Gene, Accession # | [AGAP2], Gene ID: 116986, NCBI: NP_001116244.1, UniProt: Q99490 |
| Catalog # | MBS9213113 |
| Price | $165, $370 |
| Order / More Info | CENTG1 (C-term), 850-877 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Shiba, Y., et al. J. Cell. Sci. 123 (PT 14), 2381-2390 (2010) : Zhu, Y., et al. J. Biol. Chem. 284(20):13489-13496(2009) Cai, Y., et al. Cancer Res. 69(3):819-827(2009) Tang, X., et al. Nat. Cell Biol. 10(6):698-706(2008) Liu, R., et al. Proc. Natl. Acad. Sci. U.S.A. 105(21):7570-7575(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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