RHOB Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RHOB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RHOB antibody detects endogenous levels of total RHOB. Function: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation du |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Late Endosome Membrane. Cell Membrane. Nucleus. Late Endosomal Membrane (geranylgeranylated form). Plasma Membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Tissue Specificity: Up-regulated by DNA damaging agents like H2O2 or ionizing radiation (IR). Predicted Cross Reactivity: Bovine, Horse, Sheep, Dog, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Xenopus (90%) |
| Other Names | [Aplysia RAS-related homolog 6; ARH6; ARHB; H6; MST081; MSTP081; oncogene RHO H6; ras homolog family member B; ras homolog gene family, member B; Rho cDNA clone 6; Rho related GTP binding protein RhoB Precursor; Rho-related GTP-binding protein RhoB; Rhob; RHOB_HUMAN; RHOH6] |
| Gene, Accession # | [RHOB], Gene ID: 388, NCBI: NP_004031.1, UniProt: P62745 |
| Catalog # | MBS9605892 |
| Price | $240, $280 |
| Order / More Info | RHOB Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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