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Antigenic Specificity | CREST Mouse |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology. Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same |
Immunogen | Immunogen: Synovial sarcoma translocation gene on chromosome 18-like 1 |
Other Names | n/a |
Gene, Accession # | [CREST], UniProt: O75177 |
Catalog # | MBS768204 |
Price | $320 |
Order / More Info | CREST Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |