FAS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAS
Clone[4F8H6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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DescriptionEntrez Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found
ImmunogenImmunogen: Purified recombinant fragment of human FAS expressed in E Coli.
Other Names[APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6], [APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6]
Gene, Accession #[FAS], Gene ID: 355
Catalog #MBS476264
Price$335
Order / More InfoFAS Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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