CXCR4 (NT) (HIV and chemokine receptor) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCXCR4 (NT) (HIV and chemokine receptor)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)
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DescriptionHuman immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors 1. Among them, CXCR4 (fusin, LESTR or HUMSTR) is a principal coreceptor for T-cell tropic strains of HIV-1 fusion and entry of human white blood cells2,3. CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD-4 independent infection by HIV-24,5. The -chemokine SDF-1 is the ligand for CXCR4 and prevents infection by T-tropic HIV-16,7. CXCR4 associates with the surface CD4-gp120 com
ImmunogenImmunogen: Synthetic peptide corresponding to amino acids 1 to 14 of the N terminal of the human CXCR4 receptor.
Other Names[CXCR4 (Fusin; LESTR; HUMSTR) (N Terminal)], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR]
Gene, Accession #[CXCR4], Gene ID: 7852, NCBI: NP_001008540.1, UniProt: P61073
Catalog #MBS395710
Price$510
Order / More InfoCXCR4 (NT) (HIV and chemokine receptor) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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