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Antigenic Specificity | ASK1 (Ser83) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ASK1 antibody (Ser83) detects endogenous levels of ASK1 only when phosphorylated at serine 83. ASK1, a MAP kinase kinase kinase, plays essential roles in stress-induced apoptosis. ASK1 is activated in response to a variety of stress-related stimuli through distinct mechanisms and activates MKK4 and MKK3, which in turn activate JNK and p38. Overexpression of ASK1 activates JNK and p38 and induces apoptosis in several cell types through signals involving the mitochondrial cell death pathway. |
Immunogen | Immunogen: ASK1 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human ASK1 around the phosphorylation site of serine 83 (G-S-SP-V-G) as the immunogen. |
Other Names | [Rabbit ASK1 (Ser83); ASK1; ASK1; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK-1; ASK1; MAP/ERK kinase kinase 5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Mitogen-activated protein kinase kinase kinase 5 variant] |
Gene, Accession # | [ASK1] |
Catalog # | MBS5313613 |
Price | $375 |
Order / More Info | ASK1 (Ser83) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |