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Antigenic Specificity | p70 S6 Kinase alpha (Phospho Ser434) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-p70 S6 kinase alpha (S434) Polyclonal Antibody detects endogenous levels of p70 S6 kinase alpha protein only when phosphorylated at S434. RPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for RPS6KB1 on chromosom |
Immunogen | Immunogen: Synthesized peptide derived from human p70 S6 kinase alpha around the phosphorylation site of S434 |
Other Names | [Rabbit p70 S6 kinase alpha (phospho Ser434); RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas] |
Gene, Accession # | Gene ID: 6198, NCBI: NP_001258989.1, UniProt: P23443 |
Catalog # | MBS9706714 |
Price | $130, $220, $325 |
Order / More Info | p70 S6 Kinase alpha (Phospho Ser434) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |